Comparative Analysis of Long Term Survival of Pediatric and Adult Living Donor Renal Transplantation: Single Center 10 Years Experience

Our objective was to highlight the results of comparative analysis of pediatric and adults living donor renal transplantation in a single center experience extended for more than 30 years. The study comprised of 1902 adults and 338 children aging 18 years or younger. Male sex was dominant among recipients of both groups in contrary to female sex that constituted for 75.9 % for adults and 63.6 % for pediatrics. No statistical difference was encountered for patient survival at 5 and 10 years for both groups. A significant difference was observed between pediatrics and adults 10 years graft survival. Moreover comparable patients are living enjoying good graft function for both groups at last follow up. The significant outcome predictors for graft survival for pediatrics were primary immunosuppression, acute rejection and post transplant hypertension while the corresponding factors for adults included donor age >40 years, primary immunosuppression, acute rejection, and post transplant hypertension. Multivariate analysis revealed that acute rejection sustained its impact for pediatrics while donor age >40 years, primary immunosuppression, acute rejection and post transplant hypertension still had a significant effect on outcome for the adults.